C-reactive protein

noun

C-re·​ac·​tive protein ˈsē-rē-ˈak-tiv- How to pronounce C-reactive protein (audio)
: a protein present in blood serum in various abnormal states (such as inflammation or neoplasia)
abbreviation CRP

Examples of C-reactive protein in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This is a meaningful result, because high-sensitivity C-reactive protein – hsCRP – is an inflammatory marker that can signal increased risk of cardiovascular disease. New Atlas, 17 Sep. 2025 The study found that the people who ate more red meat and did not follow the Mediterranean diet had higher levels of circulating inflammatory markers, such as interleukin-6 (IL-6) and C-reactive protein (CRP). Sandee Lamotte, CNN Money, 15 Sep. 2025 First, researchers measured high-sensitivity C-reactive protein in 12,530 healthy American women with none of the classic SMuRFs—hypertension, high cholesterol, diabetes, and smoking. Sarah Garone, Health, 9 Sep. 2025 Supplementing with mangosteen extract potentially reduces C-reactive protein (CRP) levels. Amy Brownstein, Verywell Health, 7 Aug. 2025 The results showed shockingly high levels of C-reactive protein (CRP), a protein made by the liver. Alyce Collins, MSNBC Newsweek, 28 June 2025 Physical health issues, including increases in inflammatory markers like C-reactive protein, more physical symptoms and more visits to a doctor or health center for physical illness have also been noted in research. Jess Cording, Forbes.com, 8 June 2025 Shiitake also reduces inflammation markers like CRP (C-reactive protein) and IgA (Immunoglobulin A). Boutayna Chokrane, Wired News, 28 May 2025 Those living within 4 miles of the new greenery showed 13-20% lower levels of C-reactive protein, which is produced in response to inflammation. Bill Frist, Forbes, 15 Jan. 2025

Word History

Etymology

C-polysaccharide, a polysaccharide found in the cell wall of pneumococci and precipitated by this protein, from carbohydrate

First Known Use

1952, in the meaning defined above

Time Traveler
The first known use of C-reactive protein was in 1952

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Cite this Entry

“C-reactive protein.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/C-reactive%20protein. Accessed 28 Sep. 2025.

Medical Definition

C-reactive protein

noun
C-re·​ac·​tive protein ˌsē-rē-ˌak-tiv- How to pronounce C-reactive protein (audio)
: a protein produced by the liver that is normally present in trace amounts in the blood serum but is elevated during episodes of acute inflammation (as those associated with neoplastic disease, chronic infection, or coronary artery disease)
Last Updated: - Updated example sentences
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